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Publications:

  1. Cheng, W. Y., Ho, Y. S., & Chang, R. C. C. The role of PKR as a potential pharmaceutical target for treating neuroinflammation, tau phosphorylation and cognitive dysfunctions in a peripheral inflammation model. (Under review)

  2. Cheng, W. Y., Ho, Y. S., & Chang, R. C. C. (2022). Linking circadian rhythms to microbiome-gut-brain axis in aging-associated neurodegenerative diseases. Ageing Research Reviews, 78, 101620. (Impact factor: 13.1, Q1)

  3. Wong, W. K., Lai, C. H. N., Cheng, W. Y., Tung, L. H., Chang, R. C. C., & Leung, F. K. C. (2022). Polymer–Metal Composite Healthcare Materials: From Nano to Device Scale. Journal of Composites Science, 6(8), 218. (Impact score: 3.486, Q2)

  4. Cheng, W. Y., Lam, K. L., Li, X., Kong, A. P. S., & Cheung, P. C. K. (2021). Circadian disruption-induced metabolic syndrome in mice is ameliorated by oat β- glucan mediated by gut microbiota. Carbohydrate Polymers, 267, 118216. (Impact factor: 11.2, Q1)

  5. Cheng, W. Y., Ho, Y. S., & Chang, R. C. C. (2021), The Role of PKR as a Potential Target for Treating Systemic Inflammation Triggered Neuroinflammation, Tau Phosphorylation and Cognitive Dysfunctions. Alzheimer's & Dementia, 17: e058461. 

  6. Cheng, W. Y., Ho, Y. S., & Chang, R. C. C. (2020). Laparotomy: A non‐bacterial endotoxin mouse model for investigating the impact of systemic inflammation on neuroinflammation and cognitive functions: Developing topics. Alzheimer's & Dementia, 16, e047553. 

  7. Cheng, W. Y., Lam, K. L., Kong, A. P. S., & Cheung, P. C. K. (2020). Prebiotic supplementation (beta-glucan and inulin) attenuates circadian misalignment induced by shifted light-dark cycle in mice by modulating circadian gene expression. Food Research International, 137, 109437. (Impact factor: 8.1, Q1)

  8. Lam, K. L., Cheng, W. Y., Su, Y., Li, X., Wu, X., Wong, K. H., ... & Cheung, P. C. K. (2020). Use of random forest analysis to quantify the importance of the structural characteristics of beta-glucans for prebiotic development. Food Hydrocolloids, 108, 106001. (Impact factor: 11.504, Q1)

  9. Lam, K. L., Cheng, W. Y., Yang, F., Lin, S., You, L., Chiou, J., ... & Cheung, P. C. K. (2020). Framework as a Service, FaaS: Personalized Prebiotic Development for Infants with the Elements of Time and Parametric Modelling of In Vitro Fermentation. Microorganisms, 8(5), 623. (Impact factor: 4.926, Q2)

  10. Lam, K. L., Ko, K. C., Li, X., Ke, X., Cheng, W. Y., Chen, T., ... & Cheung, P. C. K. (2019). In Vitro Infant Faecal Fermentation of Low Viscosity Barley β-Glucan and Its Acid Hydrolyzed Derivatives: Evaluation of Their Potential as Novel Prebiotics. Molecules, 24(5), 828. (Impact factor: 4.927, Q2)

  11. Cheng, W. Y., Wei, X. Q., Siu, K. C., Song, A. X., & Wu, J. Y. (2018). Cosmetic and Skincare Benefits of Cultivated Mycelia from the Chinese Caterpillar Mushroom, Ophiocordyceps sinensis (Ascomycetes). International journal of medicinal mushrooms, 20(7), 623-636.(Research article based on final year project; Impact factor: 1.921, Q3)

  12. Li, X., Zhou, J., Dong, X., Cheng, W. Y., Duan, H., & Cheung, P. C. K. (2018). In Vitro and In Vivo Photothermal Cancer Therapeutic Effects of Gold Nanorods Modified with Mushroom β-Glucan. Journal of agricultural and food chemistry, 66(16), 4091-4098. (Impact factor: 5.895, Q1)

On-going projects:

  1. Investigating the link between circadian rhythms and microbiota-gut-brain axis in the lipopolysaccharide-induced neuroinflammation model (In collaborations with HKU and CUHK)

  2. Studying the effects of prebiotics on alleviating chronodisruption and its related diseases (In collaborations with HKU and CUHK)

Experimental models:

  1. Chronodisruption mouse models

  2. Surgery (Laparotomy) mouse model

  3. Rodent brain stereotaxic injection model

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