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Publications:

  1. Cheng, W. Y., Chan, P. L., Ong, H. Y., Wong, K. H., & Chang, R. C. C. (2024). Systemic Inflammation Disrupts Circadian Rhythms and Diurnal Neuroimmune Dynamics. International Journal of Molecular Sciences, 25(13), 7458. (Impact factor: 5.6, Q1)

  2. Wu, Y. K., Xiangtian Meng, X. T., Cheng, W. Y., Yan, Z. C., Li, K. Q., Wang, J., Jiang, T. F., Zhou, F., Wong, K. H., Zhong, C. L., Dong, Y, Gao, S. (2023) Can pluripotent/multipotent stem cells reverse Parkinson’s disease progression?. Frontiers in Neuroscience, 18, 1210447. (Impact factor: 5.152)

  3. Cheng, W. Y., Ho, Y. S., & Chang, R. C. C. The role of PKR as a potential pharmaceutical target for treating neuroinflammation, tau phosphorylation and cognitive dysfunctions in a peripheral inflammation model. (Under review)

  4. Cheng, W. Y., Ho, Y. S., & Chang, R. C. C. (2022). Linking circadian rhythms to microbiome-gut-brain axis in aging-associated neurodegenerative diseases. Ageing Research Reviews, 78, 101620. (Impact factor: 13.1, Q1)

  5. Wong, W. K., Lai, C. H. N., Cheng, W. Y., Tung, L. H., Chang, R. C. C., & Leung, F. K. C. (2022). Polymer–Metal Composite Healthcare Materials: From Nano to Device Scale. Journal of Composites Science, 6(8), 218. (Impact score: 3.486, Q2)

  6. Cheng, W. Y., Lam, K. L., Li, X., Kong, A. P. S., & Cheung, P. C. K. (2021). Circadian disruption-induced metabolic syndrome in mice is ameliorated by oat β- glucan mediated by gut microbiota. Carbohydrate Polymers, 267, 118216. (Impact factor: 11.2, Q1)

  7. Cheng, W. Y., Ho, Y. S., & Chang, R. C. C. (2021), The Role of PKR as a Potential Target for Treating Systemic Inflammation Triggered Neuroinflammation, Tau Phosphorylation and Cognitive Dysfunctions. Alzheimer's & Dementia, 17: e058461. 

  8. Cheng, W. Y., Ho, Y. S., & Chang, R. C. C. (2020). Laparotomy: A non‐bacterial endotoxin mouse model for investigating the impact of systemic inflammation on neuroinflammation and cognitive functions: Developing topics. Alzheimer's & Dementia, 16, e047553. 

  9. Cheng, W. Y., Lam, K. L., Kong, A. P. S., & Cheung, P. C. K. (2020). Prebiotic supplementation (beta-glucan and inulin) attenuates circadian misalignment induced by shifted light-dark cycle in mice by modulating circadian gene expression. Food Research International, 137, 109437. (Impact factor: 8.1, Q1)

  10. Lam, K. L., Cheng, W. Y., Su, Y., Li, X., Wu, X., Wong, K. H., ... & Cheung, P. C. K. (2020). Use of random forest analysis to quantify the importance of the structural characteristics of beta-glucans for prebiotic development. Food Hydrocolloids, 108, 106001. (Impact factor: 11.504, Q1)

  11. Lam, K. L., Cheng, W. Y., Yang, F., Lin, S., You, L., Chiou, J., ... & Cheung, P. C. K. (2020). Framework as a Service, FaaS: Personalized Prebiotic Development for Infants with the Elements of Time and Parametric Modelling of In Vitro Fermentation. Microorganisms, 8(5), 623. (Impact factor: 4.926, Q2)

  12. Lam, K. L., Ko, K. C., Li, X., Ke, X., Cheng, W. Y., Chen, T., ... & Cheung, P. C. K. (2019). In Vitro Infant Faecal Fermentation of Low Viscosity Barley β-Glucan and Its Acid Hydrolyzed Derivatives: Evaluation of Their Potential as Novel Prebiotics. Molecules, 24(5), 828. (Impact factor: 4.927, Q2)

  13. Cheng, W. Y., Wei, X. Q., Siu, K. C., Song, A. X., & Wu, J. Y. (2018). Cosmetic and Skincare Benefits of Cultivated Mycelia from the Chinese Caterpillar Mushroom, Ophiocordyceps sinensis (Ascomycetes). International journal of medicinal mushrooms, 20(7), 623-636.(Research article based on final year project; Impact factor: 1.921, Q3)

  14. Li, X., Zhou, J., Dong, X., Cheng, W. Y., Duan, H., & Cheung, P. C. K. (2018). In Vitro and In Vivo Photothermal Cancer Therapeutic Effects of Gold Nanorods Modified with Mushroom β-Glucan. Journal of agricultural and food chemistry, 66(16), 4091-4098. (Impact factor: 5.895, Q1)

On-going projects:

  1. Investigating the link between circadian rhythms and microbiota-gut-brain axis in the lipopolysaccharide-induced neuroinflammation model (In collaborations with HKU and CUHK)

  2. Studying the effects of prebiotics on alleviating chronodisruption and its related diseases (In collaborations with HKU and CUHK)

Experimental models:

  1. Chronodisruption mouse models

  2. Surgery (Laparotomy) mouse model

  3. Rodent brain stereotaxic injection model

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